Alkaline Diuresis as Treatment for 2, 4-D Dimethylamine Herbicide Intoxication: A Case Report

Jindal, Nitesh and Sirohi, Tanu Raj and Kumar, Patamsetti Anil and Shoeb, Mohammad and Shabarish, Gali and Sowmya, Pediredla Sri (2022) Alkaline Diuresis as Treatment for 2, 4-D Dimethylamine Herbicide Intoxication: A Case Report. International Journal of Medical and Pharmaceutical Case Reports, 15 (4). pp. 83-87. ISSN 2394-109X

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Abstract

The use of 2, 4-D dimethylamine is expanding as a result of the rise in glyphosate and paraquat resistance in weeds [1]. Instances of 2,4D dimethylamine intoxication have been on the rise. This herbicide exhibits a range of dose-dependent harmful mechanisms, including cell membrane destruction, disruption of acetyl coenzyme A metabolism, and oxidative phosphorylation uncoupling [2]. The neurological system, heart, lungs, liver, muscles, and endocrine system may all be affected by toxic effects [3]. Results in male cases are fatal [2,4]. The usefulness of alkaline diuresis as a life-saving treatment for 2,4-D dimethylamine poisoning with severe symptoms is discussed in this paper. 2, 4-D dimethylamine intoxication can be fatal if not treated promptly. There is no particular antidote and alkaline diuresis shows good result in the patient who present with severe intoxication of 2, 4-D dimethylamine.

Item Type: Article
Subjects: STM Repository > Medical Science
Depositing User: Managing Editor
Date Deposited: 28 Feb 2023 09:33
Last Modified: 23 Oct 2024 04:02
URI: http://classical.goforpromo.com/id/eprint/2188

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