Correlation between Fructose Consumption Habits and Insulin Resistance with TyG Index Biomarkers Manifesting Metabolic Syndrome at the Elderly Monjok Integrated Services Post (Posyandu)

Aims: This study aims to prove the relationship between the habit of consuming food and/or drinks containing fructose and the occurrence of insulin resistance which manifests as metabolic syndrome in subjects at the Elderly Monjok Integrated Service Post (Posyandu), Mataram City, Indonesia.

Study Design: Observational study with a cross-sectional design.

Place and Duration of Study: Sample: Elderly Monjok Integrated Service Post (Posyandu), Mataram City, Indonesia from May to July 2022.

Methodology: The study subjects were 48 people (10 men, 38 women, age range 45-90 years old). Fructose intake was collected using the 24 hours food recall method and assessed using the nutrisurvey software. Insulin Resistance is determined by the TyG Index method. Metabolic Syndrome is determined based on the parameter of the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III).

Results: The study results showed that 52.1% of the subjects at the Elderly Monjok Integrated Service Post (Posyandu) Mataram city had insulin resistance and 62.5% had metabolic syndrome. The Chi-Square test showed that there was a significant relationship between fructose consumption habits and the occurrence of insulin resistance (ˆP=0.000) and metabolic syndrome (P=0.001).

Conclusion: This study proves that there is a significant relationship between fructose consumption habits and the occurrence of insulin resistance which manifests as metabolic syndrome, on the subjects at the Elderly Monjok Integrated Service Post (Posyandu), Mataram City, Indonesia.