Iron Deficiency Anemia: An Analysis of Mean Platelet Count Ratio of before and after Treatment in Bangladesh

Background: The most prevalent dietary-related anemia, iron deficiency anemia (IDA), is a significant global public health issue. IDA causes micro thrombosis because iron inhibits megakaryopoiesis. Thrombocytosis is improved with iron therapy.

Objective: The aim is to evaluate the role of mean platelet count ratio in iron deficient anemia diagnosis.

Methods: A retrospective analysis was conducted in the pediatric ward of the Chuadanga Sadar hospital between 11 November 2021 and 27 June 2022. 52 people in all have had iron deficiency anemia identified (35 were males, and 17 were female).

Result: The age of the patients ranged from (3-240.1) months and was 4.8 years on average. The average Hb was 8.1 g/dl, the average MCV was 60.8 fL, the average MPV was 5.7 fL, and the average MPV/PLT ratio was 0.012. The mean Hb was 10.8 g/dl, the mean MCV was 68.3 fL, the MPV was 6.6 fL, the MPV/PLT ratio was 0.02 and the p value was (0.01), considerably higher in the post-therapy group than in the pre-treatment group, and all patients responded to the treatment.

Conclusion: Based on the data at hand, the MPV/ PLT ratio demonstrated an exceptional level of performance in the diagnosis of IDA; the doctor should take note of this number. It is probable that it will be used in panels alongside more traditional biochemical markers like iron, TIBC, and serum ferritin.