Mimicry of Two Disease Guillain-Barre Syndrome and Japanese encephalitis: A Case Report

Guillian-Barre syndrome (GBS) is an acute immune-mediated inflammatory demyelinating polyneuropathy characterized by symmetrical limb weakness and areflexia preceded by an infection while Japanese encephalitis (JE) virus is a neurotropic RNA virus belonging to Flaviviridae family. GBS can have different clinical manifestations which overlaps JE. GBS secondary to JE has been reported earlier though in the incidence is low.Involvement of the peripheral nerve, areflexic paralysis, electrophysiological nerve examination and JE IgM in CSF were consistent with a diagnosis of GBS with JE. Prompt detection and diagnosis can reduce morbidity and mortality.