Deoxynivalenol: An Overview on Occurrence, Chemistry, Biosynthesis, Health Effects and Its Detection, Management, and Control Strategies in Food and Feed

Kamle, Madhu and Mahato, Dipendra Kumar and Gupta, Akansha and Pandhi, Shikha and Sharma, Bharti and Dhawan, Kajal and Vasundhara, . and Mishra, Sadhna and Kumar, Manoj and Tripathi, Abhishek Dutt and Rasane, Prasad and Selvakumar, Raman and Kumar, Arvind and Gamlath, Shirani and Kumar, Pradeep (2022) Deoxynivalenol: An Overview on Occurrence, Chemistry, Biosynthesis, Health Effects and Its Detection, Management, and Control Strategies in Food and Feed. Microbiology Research, 13 (2). pp. 292-314. ISSN 2036-7481

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Abstract

Mycotoxins are fungi-produced secondary metabolites that can contaminate many foods eaten by humans and animals. Deoxynivalenol (DON), which is formed by Fusarium, is one of the most common occurring predominantly in cereal grains and thus poses a significant health risk. When DON is ingested, it can cause both acute and chronic toxicity. Acute signs include abdominal pain, anorexia, diarrhea, increased salivation, vomiting, and malaise. The most common effects of chronic DON exposure include changes in dietary efficacy, weight loss, and anorexia. This review provides a succinct overview of various sources, biosynthetic mechanisms, and genes governing DON production, along with its consequences on human and animal health. It also covers the effect of environmental factors on its production with potential detection, management, and control strategies.

Item Type: Article
Subjects: STM Repository > Medical Science
Depositing User: Managing Editor
Date Deposited: 22 Jun 2023 05:24
Last Modified: 02 Nov 2023 06:10
URI: http://classical.goforpromo.com/id/eprint/3512

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