Evaluation the Effects of VitB6 on the Treatment of Premenstrual Syndrome: A Clinical Randomized Trial

Introduction: Premenstrual syndrome (PMS) is a regularly appearance number of symptoms during luteal phase of menstruation. The purpose of this study was, determination the effect of Vit B6 on treatment this syndrome.

Method: Two hundred girls who had moderate and severe form of premenstrual syndrome, selected randomly and divided in two groups. First group received 40 mg Vit B6 daily for three months and, and second group received daily one tablet of placebo for three months. Also they filled Rosignol Bonlender check list during use of drug. Data analyzed by SPSS version 19 and severity of symptoms compare before & after intervention in each group, and after treatment in two groups.

Result: Severity of physical, mental, physical and mental symptoms in patients who receive Vit B6 and placebo had reduced (p< 0.05).

Conclusion: Vit B6 is effective on PMS.